GLP-1 RA Adverse Event Explorer

See About page for reference for protein model. ¹

Select Target Column

Disproportionality Measure

ROR

PRR

Shows odds (ROR or PRR) of reporting an adverse event (AE) and its statistical significance (adjusted p-value) for selected column. Points on the top right indicate increased risk for the AE in the context of the selected target. Points on the top left indicate decreased risk for the AE in the context of the selected target.

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Significant Adverse Events

Download Table (CSV)

Includes AEs with adjusted p < 0.05 and |log2(ROR/PRR)| ≥ 1 in at least one facet.

Facet By (Rows)

Facet By (Columns)

Filter by Value

Select Column to Filter

Select Values to keep

Download Plot

Select & Order Columns for Sankey Plot

Available Columns

AE Category

Indication for Drug

Sex

Age Group

GLP-1 RA Drug

Outcome

Selected Columns (Drag to reorder)

Filter by Value

Select Column to Filter

Select Values to keep

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Plot Type

Select Column for Chord Diagram

Select Target Column

Cluster Heatmap

Plot Type

Target Column

Columns often have too many values to display. These controls allow for reducing the number of categories shown.

Filter by Value

Filter to our suggested AEs

Select Column to Filter

Select Values to keep

Filter by Variation

Top N Variable Categories

Group Multiples

About This Dashboard

This dashboard allows you to explore and visualize adverse event (AE) data related to GLP-1 RA therapies. Use the Visualizations tab to interact with the data.

Data Source

The data used in this dashboard is sourced from the FDA Adverse Event Reporting System (FAERS). We have processed and cleaned the data to provide meaningful insights into GLP-1 RA treatment related adverse events.

Reference

Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes
Zhang, Xin et al.
Cell Reports, Volume 36, Issue 2, 109374

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